Biovendor Human MMP 2 [Metalloproteinases] Elisa Kit

Product Description

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases, responsible for the integrity of the basement membrane (BM) via degradation of extracellular matrix and BM components. MMPs are presented in various types of cells, including cardiomyocytes, cerebral neurons, hepatocytes, and many others, thus influencing various processes. MMP-2, also called gelatinase A, is reported to play a crucial intracellular role where it cleaves several sarcomeric proteins inside cardiac myocytes during oxidative stress-induced injury.2 Elevated levels of MMP-2 (combined with MMP-9) are also associated with highly tumorigenic cancers, such as breast, gastric.